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Abstract
Andrographispaniculata(Acanthacae) is a widely used medicinal plant in China, India and South Asia. Ethanolic extract of Andrographis paniculata was assessed for its thrombolytic, anti-inflammatory activity and phytochemical screening. In vitro anti-inflammatory activity was evaluated using HRBC membrane stabilization. Aspirin was used as a standard drug for the study of anti-inflammatory activity. The ethanol extract of Andrographis paniculata showed significant activity. In thrombolytic activity using in vitro clot lysis assay method, the crude ethanol extract was found to have significant, thrombolytic test showed a maximum effect of 99.12%.while the standard streptokinase showed 90%. The plant has shown the presence of phytoconstituents such as tannins,saponin, carbohydrate which have been reported to show good protective cardio activity However, further detailed studies are required to determine the active components responsible for these effects and mechanism pathway.