Main Article Content
Abstract
Sepsis, severe sepsis, systemic inflammatory response and other related manifestations represents a medical condition with high morbidity and mortality rate globally. It was estimated that beyond 30 million people affected as reported by WHO report of 2018. Despite of satisfactory diagnostic biomarkers, loss of human life’s continues which mainly rise from infection, inflammation or due to long-term stay in ICU’s. Out of different prognostic biomarkers, PCT comes to be a reliable marker for the early diagnosis of sepsis and its related manifestations. This review gives an outlook to the explanation of sepsis – its pathophysiology, etiology, and its diagnostic marker.