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Abstract
The most powerful drug considered for treating multi-drug resistant Gram-negative bacilli infections is beta lactam ring containing antibiotics, Carbapenems. Carbapenems which are available in India for use are meropenem and imipenem. Few bacteria especially Pseudomonas species has been reported to show resistance against these antibiotics. Pseudomonas aeruginosa, Gram-negative bacilli from last decades are emerging as prevalent and potent causative agents of nosocomial infection because of emerging antimicrobial resistance due among these microorganisms.