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Abstract

Plant based vaccine production has emerged as a very feasible alternative for the biopharmaceutical industry in recent times since plants prove to be very competent and cost-effective system for generating therapeutic products. Precisely, plant-based production systems are focussed on the field of glycoengineering as it leads to development and production of diverse therapeutic molecules like antibodies or vaccines. These monoclonal antibodies will be really vital for developing disease resistance in humans and animals against existing or continuously evolving disease-causing agents like bacteria, fungi or viruses. This review provides an overview of the recent work done in the area of plant based vaccines, particularly plantibodies, by highlighting selected case studies and provides an overview of the possible applications, advantages and limitations of plantibodies. Interestingly, many plantibodies have been developed, while only some plantibodies have undergone clinical trials and very few have been approved for worldwide usage.

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