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Abstract

Diabetes mellitus (DM) is the metabolic disorder by which a lot of people are suffering all around the world. In which 94% of the diabetes cases are of Noninsulin-dependent diabetes mellitus (NIDDM). In case of NIDDM,(T2DM), irregular release of insulin formed in the β-cells of pancreatic glands or either the amount produced is not sufficient for the cellular components in the body become resistant to it (insulin resistance).In such conditions, trapping of glucose by the individual cell get reduced as it level gets increased in the systemic circulation. As insulin is produced in body were not get utilized due to insulin resistance, we are using oral hypoglycaemic agents to lower the blood glucose level. Alpha amylase enzyme (AAE)is used for the metabolism of carbohydrate and other oligosaccharides to convert monosaccharide like glucose (thus increases blood glucose level).

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