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Abstract
Stevia is a zero calorie sugar that is natural origin that takes out from leaves of plant types Stevia rebaudiana. It is easily grown in the local area of Central America and South America. Based on previous information, author has hypothesized rational behind using stevia as low calorie sweetener and harmful effects (side effects), using a non-target model organism, Drosophila melanogaster (wildtype strain, Oregon R+). Drosophila flies were reared on standard corn meal medium with yeast supplement and fed stevia dried leave and also powdered stevia (extract of stevia). Stevia dried leave and powder was also given along sulphur free sugar (which is standard component of Drosophila medium).