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Abstract
Nanoparticles (NPs) are advantageous in treating bacterial infections. Scientists found that Selenium Nanoparticles (SeNPs), owing to their unique structure and properties, may be more effective than antibiotics as they have a larger surface area and therefore can be more in contact with the external environment. The antibacterial effect of selenium may be due to the fact that at a particular concentration nano-selenium interacts with the bacterial cell surface and penetrates into the cell, thus causing damage. Some studies in recent years have suggested the use of combination of antibiotics+SeNPs, the synergistic effect of which often surpasses their individual’s inhibitory activity. In our work we performed synergetic effect of SeNPs and 3 commercial antibiotics. We found that the Nanoparticles enhanced the reaction rates of antibiotics in a synergistic mode as well as in its own way on different kinds of pathogens.